Department of Radiology, University of North Carolina School of Medicine, Chapel Hill, North Carolina, USA.
AJNR Am J Neuroradiol. 2012 Mar;33(3):399-406. doi: 10.3174/ajnr.A2499. Epub 2011 May 19.
This article is the second in a 2-part series reviewing neuroimaging in childhood SNHL. Previously, we discussed the clinical work-up of children with hearing impairment, the classification of inner ear malformations, and congenital nonsyndromic causes of hearing loss. Here, we review and illustrate the most common syndromic hereditary and acquired causes of childhood SNHL, with an emphasis on entities that demonstrate inner ear abnormalities on cross-sectional imaging. Syndromes discussed include BOR syndrome, CHARGE syndrome, Pendred syndrome, Waardenburg syndrome, and X-linked hearing loss with stapes gusher. We conclude the article with a review of acquired causes of childhood SNHL, including infections, trauma, and neoplasms.
这是一篇分为两部分的综述的第二部分，内容涉及儿童先天性感音神经性听力损失的神经影像学研究。前一篇文章中，我们讨论了儿童听力损失的临床评估、内耳畸形的分类以及先天性非综合征型听力损失的病因。本篇文章中，我们将回顾和阐述儿童先天性感音神经性听力损失最常见的综合征性遗传性和获得性病因，并重点介绍在影像学检查中显示内耳异常的疾病。本文讨论的综合征包括 Bor 综合征、 CHARGE 综合征、 Pendred 综合征、 Waardenburg 综合征和 X 连锁伴镫骨肌动症的遗传性听力损失。最后，我们将对儿童先天性感音神经性听力损失的获得性病因进行综述，包括感染、创伤和肿瘤。
