Department of Radiology, Division of Neuroradiology, University of Michigan Health System, Ann Arbor, 48109, USA.
AJNR Am J Neuroradiol. 2011 Jun-Jul;32(6):1002-3. doi: 10.3174/ajnr.A2601. Epub 2011 May 19.
Panitumumab (Vectibix), is a human monoclonal antibody EGFR antagonist indicated as a single agent for the treatment of metastatic colorectal carcinoma with disease progression on or following fluoropyrimidine, oxaliplatin, and irinotecan chemotherapy regimens. This article will present the mechanism of action as well as the clinical role for this monoclonal antibody.
帕尼单抗（Vectibix）是人源化单克隆抗体 EGFR 拮抗剂，与氟嘧啶、奥沙利铂和伊立替康化疗方案治疗后疾病进展的转移性结直肠癌的单药治疗。本文将介绍该单克隆抗体的作用机制和临床作用。
