The complex roles of histone demethylases in vivo.
作者信息
Di Stefano Luisa, Dyson Nicholas J
出版信息
Cell Cycle. 2011 Jul 1;10(13):2049-50. doi: 10.4161/cc.10.13.15758.
Abstract
摘要
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Functional antagonism between histone H3K4 demethylases in vivo.体内组蛋白 H3K4 去甲基化酶的功能拮抗作用。
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Essential functions of the histone demethylase lid.组蛋白去甲基酶 lid 的基本功能。
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Charting histone modifications and the functional organization of mammalian genomes.绘制组蛋白修饰图谱和哺乳动物基因组的功能组织结构。
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Histone chaperones ASF1 and NAP1 differentially modulate removal of active histone marks by LID-RPD3 complexes during NOTCH silencing.组蛋白伴侣ASF1和NAP1在NOTCH沉默过程中对LID-RPD3复合物去除活性组蛋白标记的调节作用存在差异。
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The H3K4 demethylase lid associates with and inhibits histone deacetylase Rpd3.H3K4去甲基化酶lid与组蛋白去乙酰化酶Rpd3结合并对其产生抑制作用。
Mol Cell Biol. 2009 Mar;29(6):1401-10. doi: 10.1128/MCB.01643-08. Epub 2008 Dec 29.
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Characterization of Drosophila melanogaster JmjC+N histone demethylases.黑腹果蝇JmjC + N组蛋白去甲基化酶的特性分析
Nucleic Acids Res. 2008 May;36(9):2852-63. doi: 10.1093/nar/gkn098. Epub 2008 Mar 29.
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Cell and molecular biology of Notch.Notch的细胞与分子生物学
J Endocrinol. 2007 Sep;194(3):459-74. doi: 10.1677/JOE-07-0242.
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Heterochromatin formation in Drosophila is initiated through active removal of H3K4 methylation by the LSD1 homolog SU(VAR)3-3.果蝇中异染色质的形成是通过LSD1同源物SU(VAR)3-3主动去除H3K4甲基化来启动的。
Mol Cell. 2007 Apr 13;26(1):103-15. doi: 10.1016/j.molcel.2007.02.025.
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