Rheumatology and Rehabilitation Department, Mansoura Faculty of Medicine, Mansoura University, Mansoura, Egypt.
Clin Rheumatol. 2011 Dec;30(12):1527-34. doi: 10.1007/s10067-011-1770-x. Epub 2011 May 20.
Since vascular risk factors that predispose to vertebrobasilar ischemia are common findings in elderly, cervical spondylosis-which is also common in such age group-as a cause of vertigo is sometimes considered as a myth. The purpose of this study is to investigate the effect of cervical spondylosis on blood flow velocity of VAs during cervical rotation and to identify the possible association of vertigo with the decreased blood flow velocity through VAs during head rotation in these patients. The incidence of cervical spondylosis was estimated in patients with and without vertigo. Patients with vertigo proved to have spondylosis are further compared with patients having spondylosis but not complaining of vertigo and patients who neither have spondylosis nor complain of vertigo who served as controls. Plain cervical radiography was used to evaluate cervical degenerative changes using cervical degenerative index. Color duplex sonography was used to measure vertebral artery blood flow with the cervical spine in the neutral position then with 60° rotation and 30° extension to measure the opposite vertebral artery. A significantly higher prevalence of cervical spondylosis was found among patients complaining of vertigo than those in non-vertigo group (71.4% vs. 32.9%, respectively). Furthermore, among patients with cervical spondylosis, patients having vertigo showed significantly more evident degenerative changes (P = 0.003). Despite Doppler ultrasound examination with head in neutral position was similar in all groups; cervical spondylosis patients with vertigo had statistically significant lower blood flow parameters with contralateral head rotation in the left and right vertebral arteries than cervical spondylosis patients without vertigo and controls. The decreased vertebral artery blood flow that occurs with cervical rotation can be observed in patients with cervical spondylosis. In patients with high-grade cervical spondylosis with more extensive osteophyte formation, the decreased blood flow becomes prominent and symptomatic presenting as vertigo.
由于导致椎基底动脉缺血的血管危险因素在老年人中很常见,因此颈椎病——在该年龄段也很常见——作为眩晕的原因,有时被认为是一种误解。本研究旨在探讨颈椎病对颈椎旋转时椎动脉血流速度的影响,并确定在这些患者中,头部旋转时椎动脉血流速度降低与眩晕之间的可能关联。评估了有眩晕和无眩晕患者的颈椎病发病率。患有眩晕且被证实患有颈椎病的患者与有颈椎病但无眩晕症状的患者以及既无颈椎病也无眩晕症状的患者进行进一步比较,后者作为对照组。颈椎退行性指数用于颈椎正位片评估颈椎退行性改变。彩色双功超声用于测量中立位、60°旋转和 30°伸展时椎动脉血流,以测量对侧椎动脉。结果发现,有眩晕症状的患者颈椎病发病率明显高于无眩晕症状的患者(分别为 71.4%和 32.9%)。此外,在颈椎病患者中,有眩晕的患者退行性改变更为明显(P=0.003)。尽管中立位头部的多普勒超声检查在所有组中均相似;但与无眩晕的颈椎病患者和对照组相比,有眩晕的颈椎病患者在左侧和右侧椎动脉头部旋转时,椎动脉血流参数明显更低,具有统计学意义。颈椎病患者颈椎旋转时可观察到椎动脉血流减少。在有高级别颈椎病且有更广泛骨赘形成的患者中,血流减少更为明显,并出现眩晕等症状。