Laboratoire de Chimie Organique et Spectroscopies Avancées (LCOSA), UMR 7515 au CNRS, Ecole de Chimie, Polymères, Matériaux de Strasbourg (ECPM), 25 rue Becquerel, 67087 Strasbourg, Cedex 02, France.
Org Lett. 2011 Jun 17;13(12):3072-5. doi: 10.1021/ol200969r. Epub 2011 May 20.
Water-soluble BODIPY dyes have been readily obtained by introduction of phosphonate fragments either on the boron for the green and yellow emitting dyes or on the side chain for the red emitting dyes. Hydrolysis of the phosphonate is realized at the end of the reaction sequence and allows isolation of the targets by precipitation. All these novel dyes are soluble and fluorescent in water with quantum yields in the 23-59% range and emission wavelength spanning from 667 to 509 nm.
水溶性 BODIPY 染料可以通过在硼原子上引入膦酸酯片段（对于绿色和黄色发光染料）或在侧链上引入膦酸酯片段（对于红色发光染料）来轻易获得。膦酸酯的水解是在反应序列的最后一步进行的，并且可以通过沉淀来分离目标产物。所有这些新型染料在水中都具有良好的溶解性和荧光性，量子产率在 23-59%范围内，发射波长范围从 667nm 到 509nm。
