高水溶性中性 BODIPY 染料，具有可控的荧光量子产率。
Highly water-soluble neutral BODIPY dyes with controllable fluorescence quantum yields.
机构信息
Department of Chemistry, Michigan Technological University, Houghton, Michigan 49931, USA.
出版信息
Org Lett. 2011 Feb 4;13(3):438-41. doi: 10.1021/ol102758z. Epub 2010 Dec 22.
Abstract
A series of novel highly water-soluble neutral BODIPY dyes have been obtained by functionalization of BODIPY dyes with branched oligo(ethylene glycol)methyl ether groups at positions 8, 2 and 6 or 4 and 4'. Use of an ortho-substituent group of branched oligo(ethylene glycol)methyl ether on the meso-phenyl ring of BODIPY dyes and replacement of the fluorine atoms of BODIPY dyes at positions 4 and 4' with methyloxy or ethynyl subunits significantly enhance fluorescence quantum yields of BODIPY dyes.
摘要
一系列新型高度水溶性中性 BODIPY 染料已通过在 BODIPY 染料的 8、2 和 6 位或 4 和 4'位用支化聚（乙二醇）甲醚基团官能化而获得。在 BODIPY 染料的间苯环上使用支化聚（乙二醇）甲醚的邻位取代基和用甲氧基或乙炔基取代 BODIPY 染料的 4 和 4'位的氟原子，显著提高了 BODIPY 染料的荧光量子产率。
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