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[肾血流量作为去神经支配后代偿性肥大过程中营养性影响实现的一个因素]

[Renal blood flow as a factor in the realization of trophic influences during compensatory hypertrophy under denervation].

作者信息

Barinov E F, Kot A G, Kladko I V

出版信息

Fiziol Zh SSSR Im I M Sechenova. 1990 Jan;76(1):108-14.

PMID:2159899
Abstract

In the Wistar rats, the effect of nervous decentralization of a single kidney on the changes of local blood flow in the cortex and medulla, was studied. Phasic changes of the intraorganic [correction of interorgan] hemodynamics involving a cortical perfusion increase during 15 days followed by a progressive decrease of the local blood flow, were recorded. The redistribution in the kidney blood flow involved a decrease of the tissue blood flow in the cortex within 30 days along with a rise in the local medullary blood flow. The cortical blood flow decrease was due to a changed reactivity of the denervated kidney's arterioles and lesion of the tubulo-interstitium in the cortex.

摘要

在Wistar大鼠中,研究了单侧肾脏神经去传入对皮质和髓质局部血流变化的影响。记录到器官内[纠正为器官间]血流动力学的阶段性变化,包括15天内皮质灌注增加,随后局部血流逐渐减少。肾脏血流的重新分布涉及30天内皮质组织血流减少,同时局部髓质血流增加。皮质血流减少是由于去神经支配肾脏的小动脉反应性改变以及皮质肾小管间质损伤所致。

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