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[自主神经支配部分受损时单肾局部血流的变化]

[Changes in the local blood flows of the single kidney with partial impairment of the autonomic innervation].

作者信息

Barinov E F, Kot A G, Onishchenko N A

出版信息

Biull Eksp Biol Med. 1989 Mar;107(3):283-5.

PMID:2653450
Abstract

The changes of cortical and intramedullary blood flow of the remaining after nephrectomy kidney under the condition of guanethidine sympathectomy and continuous pharmacological blockade of parasympathetic mediation by atropine were studied in chronic experiments on Wistar line rats in dynamics at 4, 7, 15, 30, 60, 90 and 120 days. Decrease in cortical and increase of intramedullary peritubular blood flow were noted in both experimental series, that is both blockade of sympathetic and parasympathetic nerves after 15 days. The conclusion was made that blood flow redistribution is a universal mechanisms of single kidney adaptation to its neurogenic impairments.

摘要

在Wistar系大鼠的慢性实验中,在4、7、15、30、60、90和120天的动态过程中,研究了胍乙啶交感神经切除术和阿托品持续药理学阻断副交感神经介导条件下肾切除术后剩余肾脏的皮质和髓内血流变化。在两个实验组中均观察到皮质血流减少和髓内肾小管周围血流增加,即在15天后交感神经和副交感神经均被阻断。得出的结论是,血流重新分布是单个肾脏适应其神经源性损伤的普遍机制。

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