Independent Medical and Psychological Services, Taunton, United Kingdom.
Psychiatry Res. 2011 Jul 30;188(2):245-52. doi: 10.1016/j.psychres.2011.04.012. Epub 2011 May 19.
This study investigated, firstly, the rate of posttraumatic stress disorder (PTSD) and the level of psychological well-being amongst people with chronic fatigue syndrome (CFS); and secondly, the extent to which illness cognitions, defence styles and PTSD symptom severity related to fatigue severity and psychological well-being. Seventy-eight participants with a diagnosis of CFS completed the Chalder Fatigue Scale, the General Health Questionnaire-28, the Posttraumatic Stress Diagnostic Scale, the Illness Cognition Questionnaire and the Defence Style Questionnaire. Fifty-nine participants were recruited from the general public to form the non-fatigued control group. CFS participants had significantly higher levels of PTSD symptoms, lower levels of psychological well-being and more traumatic life events compared to the non-fatigued controls. Trauma exposure and PTSD severity both predicted CFS status. However, regression analyses demonstrated no significant relationship between PTSD symptoms and fatigue severity or the degree of psychological well-being. 'Helplessness' predicted both physical and mental fatigue and psychological well-being, whilst the 'mature' defence styles predicted fatigue severity only. The results offer support to previous research showing that the rate of traumatic life events and PTSD are significantly higher amongst the CFS population. The lack of relationship between PTSD symptoms and fatigue severity or psychological well-being indicates that these processes may operate independently of one another, via different appraisal processes. This study focused on fatigue severity, but it may be that the role of pain in CFS is a key element in the previously reported association between PTSD and CFS.
本研究首先调查了慢性疲劳综合征 (CFS) 患者创伤后应激障碍 (PTSD) 的发生率和心理健康水平;其次,研究了疾病认知、防御方式和 PTSD 症状严重程度与疲劳严重程度和心理健康之间的关系。78 名 CFS 患者完成了 Chalder 疲劳量表、一般健康问卷-28、创伤后应激诊断量表、疾病认知问卷和防御方式问卷。从普通人群中招募了 59 名参与者作为非疲劳对照组。与非疲劳对照组相比,CFS 患者 PTSD 症状明显更严重,心理健康水平更低,创伤性生活事件更多。创伤暴露和 PTSD 严重程度都预测了 CFS 状态。然而,回归分析表明,PTSD 症状与疲劳严重程度或心理健康程度之间没有显著关系。“无助感”预测了身体和精神疲劳以及心理健康,而“成熟”的防御方式仅预测了疲劳严重程度。这些结果支持了先前的研究,表明创伤性生活事件和 PTSD 的发生率在 CFS 人群中显著更高。PTSD 症状与疲劳严重程度或心理健康之间缺乏关系表明,这些过程可能通过不同的评估过程彼此独立运作。本研究侧重于疲劳严重程度,但 CFS 中的疼痛可能是 PTSD 和 CFS 之间先前报告的关联的一个关键因素。