Department of Medicine and Epidemiology, School of Veterinary Medicine, University of California, Davis, CA 95616, USA.
Prev Vet Med. 2011 Aug 1;101(1-2):18-34. doi: 10.1016/j.prevetmed.2011.04.002. Epub 2011 May 23.
The Standards for Reporting of Diagnostic Accuracy (STARD) statement (www.stard-statement.org) was developed to encourage complete and transparent reporting of key elements of test accuracy studies in human medicine. The statement was motivated by widespread evidence of bias in test accuracy studies and the finding that incomplete or absent reporting of items in the STARD checklist was associated with overly optimistic estimates of test performance characteristics. Although STARD principles apply broadly, specific guidelines do not exist to account for unique considerations in livestock studies such as herd tests, potential use of experimental challenge studies, a more diverse group of testing purposes and sampling designs, and the widespread lack of an ante-mortem reference standard with high sensitivity and specificity. The objective of the present study was to develop a modified version of STARD relevant to paratuberculosis (Johne's disease) in ruminants. Examples and elaborations for each of the 25 items were developed by a panel of experts using a consensus-based approach to explain the items and underlying concepts. The new guidelines, termed STRADAS-paraTB (Standards for Reporting of Animal Diagnostic Accuracy Studies for paratuberculosis), should facilitate improved quality of reporting of the design, conduct and results of paratuberculosis test accuracy studies which were identified as "poor" in a review published in 2008 in Veterinary Microbiology.
诊断准确性研究报告的标准（STARD）声明（www.stard-statement.org）是为了鼓励全面、透明地报告人类医学中测试准确性研究的关键要素而制定的。该声明的动机是广泛存在的测试准确性研究中的偏差证据，以及发现 STARD 清单中项目的不完整或不存在报告与测试性能特征的过于乐观的估计有关。尽管 STARD 原则广泛适用，但对于家畜研究，如群体检测、可能使用实验性挑战研究、更多样化的检测目的和抽样设计，以及广泛缺乏高灵敏度和特异性的生前参考标准等独特考虑因素，并没有具体的指南。本研究的目的是开发一个适用于反刍动物副结核病（约翰氏病）的 STARD 修订版。一个专家组使用基于共识的方法，为每个 25 个项目开发了示例和详细说明，以解释项目和基本概念。新的指南称为 STRADAS-paraTB（副结核病动物诊断准确性研究报告的标准），应该有助于提高 2008 年在兽医微生物学杂志上发表的一篇综述中被评为“较差”的副结核病测试准确性研究的报告质量。
