Division of Pharmacoepidemiology and Pharmacoeconomics, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA 02120, USA.
J Am Pharm Assoc (2003). 2011 Jul-Aug;51(4):492-8. doi: 10.1331/JAPhA.2011.10006.
To explore caregiver adherence to chronic medications and predictors of appropriate medication use.
Descriptive, nonexperimental, cross-sectional study.
United States in May 2009.
2,000 adults randomly selected from a large national consumer panel.
Web-based survey of community pharmacy patients.
Self-reported medication adherence.
21% of those invited (3,775) responded to the survey invitation. Of the 2,000 individuals who were eligible to participate, 38% described themselves as caregivers. Among caregivers, 45% agreed that they were more likely to forget their own medications than medications for their caregivees. Caregivers were 10% more likely to forget to take their medications, 11% more likely to stop taking medications if they felt well, and 13% more likely to forget to refill their medications than noncare-givers (P < 0.001 for all). In fully adjusted models, caregivers had 36% greater odds (95% CI 0.52-0.79) of reporting that they were nonadherent compared with noncare-givers and increased medication use among caregivees was associated with worse adherence among caregivers (P < 0.05).
Medication nonadherence was common in this population, and caregivers were more likely to report poor medication adherence than noncaregivers. Considering that caregivers often engage health professionals, physicians and pharmacists may choose to screen for caregiving status. Pharmacists are uniquely positioned to intervene to enhance appropriate medication adherence.
探索照顾者对慢性药物的依从性和适当用药的预测因素。
描述性、非实验性、横断面研究。
2009 年 5 月的美国。
从一个大型全国消费者小组中随机抽取的 2000 名成年人。
社区药房患者的基于网络的调查。
自我报告的药物依从性。
邀请的 21%（3775 人）对调查邀请做出了回应。在有资格参加的 2000 名个人中，38%的人自称是照顾者。在照顾者中，45%的人认为自己比照顾者更有可能忘记自己的药物。照顾者忘记服用自己的药物的可能性增加了 10%，感觉良好时停止服用药物的可能性增加了 11%，忘记补药的可能性增加了 13%（所有 P 值均<0.001）。在完全调整的模型中，与非照顾者相比，照顾者报告不依从的可能性高 36%（95%CI 0.52-0.79），照顾者对照顾者的药物使用增加与照顾者的药物依从性下降相关（P<0.05）。
在该人群中，药物不依从很常见，照顾者比非照顾者更有可能报告药物依从性差。考虑到照顾者经常与卫生专业人员接触，医生和药剂师可能会选择筛查照顾者的身份。药剂师处于独特的地位，可以进行干预以提高适当的药物依从性。
