UCL, Institute of Ophthalmology, Division of Epidemiology and Genetics, Bath Street, London EC1V 9EL, UK.
Br J Ophthalmol. 2012 Mar;96(3):345-9. doi: 10.1136/bjo.2011.204040. Epub 2011 May 20.
To address the absence from the public health ophthalmology literature of age- and sex-specific prevalence and related resource use for diabetic macular oedema (DMO) in England, UK.
Calculation of age- and sex-specific rates from primary source clinical data, and application to the demographic structure of England to estimate the number of cases affected by DMO. A public health commissioner and provider of social care perspective was adopted in a standard cost of illness study.
The number of people with diabetes in England in 2010 was estimated at 2,342,951 of which 2,334,550 were aged ≥ 12 years. An estimated 166,325 (7.12%) had DMO in one or both eyes, and of these, 64,725 individuals had clinically significant DMO reducing the visual acuity to poorer than 6/6 in at least one eye. The overall health and social care costs in 2010, on the pathway from screening to rehabilitation and care in the home, are estimated at £116,296,038.
The outcomes of this study should alert public health commissioners and clinical providers to the burden of DMO. The methods employed should also encourage the use of clinical ophthalmic data at the interface between local population and hospital-based recording systems.
解决英国公共卫生眼科学文献中缺乏针对糖尿病性黄斑水肿（DMO）的年龄和性别特异性患病率及相关资源利用情况的问题。
从原始临床数据源计算年龄和性别特异性比率，并将其应用于英格兰的人口结构，以估计受 DMO 影响的病例数。采用公共卫生专员和社会护理提供者的视角进行标准疾病成本研究。
2010 年英格兰的糖尿病患者人数估计为 2342951 人，其中≥12 岁的患者为 2334550 人。估计有 166325 人（7.12%）一只或两只眼睛患有 DMO，其中 64725 人患有临床显著的 DMO，导致至少一只眼睛的视力低于 6/6。在 2010 年，从筛查到康复和家庭护理的路径上，总体健康和社会护理成本估计为 116296038 英镑。
本研究的结果应引起公共卫生专员和临床提供者对 DMO 负担的关注。所采用的方法还应鼓励在本地人群和基于医院的记录系统之间使用临床眼科数据。
