Department of Anesthesiology and Pain Medicine, University of Washington, and Seattle Children's Hospital, Seattle, Washington 98105, USA.
Curr Opin Anaesthesiol. 2011 Aug;24(4):433-8. doi: 10.1097/ACO.0b013e328347f931.
Radiation oncology is a cornerstone in the treatment of cancer in children. Although painless, there is a requirement for the child to lie still by themselves in the radiation treatment room, for multiple daily or twice daily treatments for up to 6 weeks. Anesthesia or sedation is usually necessary to achieve this in younger children. This review provides a brief update of the latest developments in radiation oncology and describes the current best practice in anesthesia for these children.
Advances in radiation therapy and the newer modality of proton beam therapy have enabled radiation oncologists to target tumors more successfully, while avoiding damage to normal tissues. Anesthesiologists are increasingly being asked to provide sedation or anesthesia to ensure a completely immobile patient during radiation therapy.
In the vast majority of cases, total intravenous anesthesia or sedation using propofol ensures that the child remains immobile, whilst maintaining spontaneous respiration, an unobstructed airway, and cardiovascular stability.
放射肿瘤学是治疗儿童癌症的基石。虽然无痛苦,但为了在 6 周内每天多次或每天两次接受治疗,需要孩子自己在放射治疗室中保持静止不动。对于年龄较小的孩子,通常需要麻醉或镇静才能达到这一目的。本文简要介绍了放射肿瘤学的最新进展,并描述了目前对这些儿童进行麻醉的最佳实践。
放射治疗的进步和质子束治疗的新模式使放射肿瘤学家能够更成功地靶向肿瘤,同时避免对正常组织造成损害。麻醉师越来越多地被要求提供镇静或麻醉,以确保在放射治疗过程中患者完全不动。
在绝大多数情况下,使用丙泊酚进行全静脉麻醉或镇静可确保孩子保持不动,同时保持自主呼吸、气道通畅和心血管稳定。