Moin Payam, Khalighinejad Nima, Yusefi Arash, Farajzadegan Ziba, Barekatain Majid
General Practitioner, School of Medicine, Isfahan University of Medical sciences, Hezarjerib Street, Isfahan, Iran.
Int J Prev Med. 2011 Apr;2(2):82-7.
Glasgow Outcome Scale Extended (GOSE), Galveston Amnesia and orientation Test (GOAT) and Disability Rating Scale (DRS) are three popular outcome measure tools used principally in traumatic brain injury (TBI) patients. We conducted this study to provide a Farsi version of these outcome scales for use in Iran.
Following a comprehensive literature review, Farsi transcripts were prepared by "forward-backward" translation and reviewed by subject experts. After a pretest on a few patients, the final versions were obtained. 38 patients with closed head injury were interviewed simultaneously by two interviewers. Main statistics used to assess validity and reliability included "Factor analysis" for construct validity, Cronbach's alpha for internal consistency, and Pearson Correlation and Kappa Coefficient for inter-rater agreement.
Factor analysis for Farsi-GOAT (FGOAT) revealed 5 independent factors with a total distribution variance of 80.2%. For Farsi-DRS (FDRS), 3 independent factors were found with a 92.3% variance. The Cronbach's alpha (95% confidence interval) was 0.84 (0.763- 0.919) and 0.91 (0.901-0.919) for FGOAT and FDRS, respectively. Pearson Correlation between total scores of two raters was 0.98 and 0.97 for FGOAT and FDRS, in order. Kappa coefficient (95% CI) between outcome rankings of raters was 0.73 (0.618-0.852) and 0.68 (0.594-0.770) for FGOAT and FDRS, respectively. As for Farsi-GOSE scale, Kappa value was 0.4 (0.285-0.507) for 8-level outcome ranking and improved to 0.7 (0.585-0.817) for 5-level scale. We found a good correlation between FDRS and FGOSE predicted prognoses (Spearman's rho= 0.74, 95% CI: 0.676-0.802).
FDRS and FGOAT had appropriate validity and reliability. The 8-level outcome FGOSE scale disclosed a low inter-rater agreement, but a suitable observer agreement was achieved when the 5-level outcome was applied.
格拉斯哥扩展预后量表(GOSE)、加尔维斯顿失忆与定向力测试(GOAT)以及残疾评定量表(DRS)是主要用于创伤性脑损伤(TBI)患者的三种常用预后评估工具。我们开展本研究以提供这些预后量表的波斯语版本供伊朗使用。
在全面的文献综述之后,通过“前后”翻译编制波斯语文本,并由主题专家进行审核。在对少数患者进行预测试后,获得最终版本。由两名访谈者同时对38例闭合性颅脑损伤患者进行访谈。用于评估效度和信度的主要统计方法包括用于结构效度的“因子分析”、用于内部一致性的克朗巴哈系数,以及用于评分者间一致性的皮尔逊相关系数和卡帕系数。
波斯语版GOAT(FGOAT)的因子分析显示5个独立因子,总分布方差为80.2%。对于波斯语版DRS(FDRS),发现3个独立因子,方差为92.3%。FGOAT和FDRS的克朗巴哈系数(95%置信区间)分别为0.84(0.763 - 0.919)和0.91(0.901 - 0.919)。两名评分者总分之间的皮尔逊相关系数,FGOAT和FDRS依次为0.98和0.97。评分者结果排名之间的卡帕系数(95%CI),FGOAT和FDRS分别为0.73(0.618 - 0.852)和0.68(0.594 - 0.770)。至于波斯语版GOSE量表,8级结果排名的卡帕值为0.4(0.285 - 0.507),5级量表时提高到0.7(0.585 - 0.817)。我们发现FDRS与FGOSE预测预后之间存在良好相关性(斯皮尔曼等级相关系数 = 0.74,95%CI:0.676 - 0.802)。
FDRS和FGOAT具有适当的效度和信度。8级结果的FGOSE量表显示评分者间一致性较低,但应用5级结果时达成了合适的观察者一致性。