Mitochondrial dysfunction during sepsis: still more questions than answers.
作者信息
Exline Matthew C, Crouser Elliott D
出版信息
Crit Care Med. 2011 May;39(5):1216-7. doi: 10.1097/CCM.0b013e31821487cb.
Abstract
摘要
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Bioenergetic failure of human peripheral blood monocytes in patients with septic shock is mediated by reduced F1Fo adenosine-5'-triphosphate synthase activity.败血症性休克患者外周血单核细胞的生物能量衰竭是由 F1Fo 腺苷-5'-三磷酸合酶活性降低介导的。
Crit Care Med. 2011 May;39(5):1056-63. doi: 10.1097/CCM.0b013e31820eda5c.
2
Temporal increase of platelet mitochondrial respiration is negatively associated with clinical outcome in patients with sepsis.血小板线粒体呼吸的时间增加与脓毒症患者的临床结局呈负相关。
Crit Care. 2010;14(6):R214. doi: 10.1186/cc9337. Epub 2010 Nov 24.
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Survival in critical illness is associated with early activation of mitochondrial biogenesis.危重病患者的存活率与线粒体生物发生的早期激活有关。
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