葡聚糖免疫刺激剂、佐剂、潜在药物。
Glucan-immunostimulant, adjuvant, potential drug.
作者信息
Vetvicka Vaclav
机构信息
Vaclav Vetvicka, Department of Pathology, University of Louisville, Louisville, KY 40202, United States.
出版信息
World J Clin Oncol. 2011 Feb 10;2(2):115-9. doi: 10.5306/wjco.v2.i2.115.
Abstract
β-glucans belong to a group of biologically active natural compounds called biological response modifiers. These substances represent highly conserved structural components of cell walls in fungi, yeast, grain and seaweed. Despite almost 160 years of intensive research, the exact mechanisms of their action remain unsolved. The significant role of glucans in cancer treatment, infection immunity, stress reduction and restoration of damaged bone marrow has already been established. The present review focuses on the various less known but potentially significant roles glucans might play in medicine. In summary, glucan might represent the most important natural immunomodulator.
摘要
β-葡聚糖属于一类被称为生物反应调节剂的生物活性天然化合物。这些物质是真菌、酵母、谷物和海藻细胞壁中高度保守的结构成分。尽管经过了近160年的深入研究，其确切作用机制仍未解决。葡聚糖在癌症治疗、感染免疫、减轻压力和受损骨髓恢复方面的重要作用已经得到证实。本综述重点关注葡聚糖在医学中可能发挥的各种鲜为人知但潜在重要的作用。总之，葡聚糖可能是最重要的天然免疫调节剂。
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