Wardlaw Russell, Victor David, Feagans Jacob, Smith James
Department of Gastroenterology, Ochsner Clinic Foundation, New Orleans, LA.
Ochsner J. 2007 Fall;7(3):125-8.
Pill-induced esophageal injury remains an under-recognized event despite its potentially devastating consequences. Most cases are due to nonsteroidal anti-inflammatory drugs, antibiotics, or bisphosphonates, and symptoms usually resolve upon discontinuation of the medication. Reported herein is the case of an elderly woman who experienced prolonged impaction of a calcium tablet in the upper esophagus. She reported breaking the nonprescription pill in half prior to ingestion due to its large size. Subsequently, a severe esophageal stricture developed. We are unaware of any previous cases of esophageal stricture due to an impacted tablet containing primarily calcium, among other minerals. This is relevant, as patients are being advised by both their physicians and the lay press to increase calcium intake. It also highlights the importance of proper instruction and cautions for taking both prescription and over-the-counter preparations. Management of patients with suspected pill impaction is discussed.
尽管药物性食管损伤可能会带来严重后果,但它仍然是一个未得到充分认识的事件。大多数病例是由非甾体抗炎药、抗生素或双膦酸盐引起的,症状通常在停药后会缓解。本文报告了一例老年女性病例,其食管上段出现钙片长期嵌顿的情况。她报告称,由于非处方钙片尺寸较大,在服用前将其掰成了两半。随后,出现了严重的食管狭窄。我们尚未发现此前有任何因主要含钙质及其他矿物质的片剂嵌顿而导致食管狭窄的病例。这一点很重要,因为医生和大众媒体都在建议患者增加钙的摄入量。它还凸显了正确指导以及对服用处方药和非处方药的注意事项的重要性。文中还讨论了疑似药丸嵌顿患者的处理方法。