Sir Peter Mansfield Magnetic Resonance Centre, School of Physics and Astronomy, University of Nottingham, Nottingham, United Kingdom.
Magn Reson Med. 2011 Nov;66(5):1498-509. doi: 10.1002/mrm.22926. Epub 2011 May 20.
This study shows that larger rates of change of gradient with time (dG/dt) can be achieved at the threshold for peripheral nerve stimulation by applying a uniform concomitant field varying synchronously with a transverse field gradient and that this increase may be achieved without significant reduction of the spatial extent of the region over which imaging can be carried out. Realization of similar benefits through application of a uniform, z-directed field varying synchronously with an axial gradient is also demonstrated. The design and construction of transverse and axial coil arrangements is described, along with the results of volunteer studies that were carried out on 20 subjects, with the subjects positioned with four different regions (head, heart, hips, and knees) centered in the coils. These experiments were carried out at zero-field on a prototype system in which the coils were not actively shielded. The uniform concomitant field coil was not torque balanced. The increase in the rate of change of gradient at the threshold for peripheral nerve stimulation that could be achieved by the addition of the uniform field depends on body position and was larger for the transverse coils (head = × 1.9 ± 0.6; heart = × 0.9 ± 0.3; hips = × 1.4 ± 0.4; knees = × 1.5 ± 0.4) than for the axial coils (head = × 1.5 ± 0.6; heart = × 0.8 ± 0.3; hips = × 1.3 ± 0.4; knees = × 1.1 ± 0.3).
本研究表明,通过施加与横向磁场梯度同步变化的均匀伴随场,可以在达到外周神经刺激阈值时实现更大的梯度随时间的变化率(dG/dt),并且可以在不显著减小可以进行成像的区域的空间范围的情况下实现这种增加。通过施加与轴向梯度同步变化的均匀、z 方向磁场也可以实现类似的益处。本文描述了横向和轴向线圈排列的设计和结构,以及在 20 名志愿者上进行的研究结果,志愿者的四个不同部位(头部、心脏、臀部和膝盖)位于线圈的中心。这些实验是在原型系统上进行的,该系统在零磁场下运行,线圈未进行主动屏蔽。均匀伴随场线圈未进行转矩平衡。通过添加均匀场可以实现的外周神经刺激阈值处梯度随时间的变化率的增加取决于体位,横向线圈的增加幅度更大(头部 = × 1.9 ± 0.6;心脏 = × 0.9 ± 0.3;臀部 = × 1.4 ± 0.4;膝盖 = × 1.5 ± 0.4),而轴向线圈的增加幅度较小(头部 = × 1.5 ± 0.6;心脏 = × 0.8 ± 0.3;臀部 = × 1.3 ± 0.4;膝盖 = × 1.1 ± 0.3)。