Faculty of Medicine, University of Bergen, Bergen, Norway.
Scand Cardiovasc J. 2011 Aug;45(4):247-51. doi: 10.3109/14017431.2011.582139. Epub 2011 May 23.
The difference in survival between genders after coronary artery bypass surgery (CABG) have been studied with varying results. We wanted to investigate gender and age specific relative survival in the CABG population. Risk factors increasing hazard of death in female patients were isolated.
Retrospectively, 6699 primary isolated CABG procedures were investigated. Long-term survival compared to expected survival in the background population was described through Kaplan-Meier plots. Two subgroups of female patients were described through baseline characteristics, t-tests, odds ratio and multivariate analysis to investigate risk factors for death within one year after surgery.
Women had significantly decreased relative long-term survival compared to men in this study. Relative survival was lower in patients below 70 years of age at surgery with about the same gender difference. Low ejection fraction, left main stem stenosis and reduced renal function were found to increase risk of death within one year after CABG in women, while body size quantified by body surface area (BSA) did not.
Relative long-term survival after CABG was poorer in female compared to male patients. This tendency was kept or strengthened when only those less than 70 years of age at surgery were investigated. Lower female survival was most likely due to more comorbidity in female patients. Relative survival was lower in patients <70 years.
冠状动脉旁路移植术（CABG）后男女之间的生存差异已有研究，但结果不一。我们旨在调查 CABG 人群中性别和年龄特异性相对生存率。孤立女性患者死亡风险增加的危险因素。
回顾性分析了 6699 例原发性单纯 CABG 手术。通过 Kaplan-Meier 图描述长期生存与背景人群预期生存的比较。通过基线特征、t 检验、比值比和多因素分析描述了两组女性患者，以调查术后 1 年内死亡的危险因素。
与男性相比，女性的长期相对生存率显著降低。手术时年龄低于 70 岁的患者相对生存率较低，且性别差异相同。低射血分数、左主干狭窄和肾功能降低被发现增加了女性 CABG 术后 1 年内死亡的风险，而通过体表面积（BSA）量化的体型则没有。
与男性患者相比，CABG 后女性患者的长期相对生存率较差。当仅调查手术时年龄小于 70 岁的患者时，这种趋势保持或增强。女性较低的生存率可能是由于女性患者的合并症更多。年龄<70 岁的患者相对生存率较低。
