Department of Dermatology, Sir Charles Gairdner Hospital, Perth, Western Australia, Australia.
Australas J Dermatol. 2011 May;52(2):e7-10. doi: 10.1111/j.1440-0960.2010.00632.x. Epub 2010 Mar 31.
Malignant melanoma has previously been reported with paraneoplastic syndromes including dermatomyositis. We report a case involving a 34-year-old woman who presented with a persistent skin rash over her neck and upper body, with clinical features suggestive of dermatomyositis. The patient had a history of a right shoulder lesion that was previously removed; a solitary axillary lymph node was detected on additional imaging and biopsy results were consistent with malignant melanoma. The following year, surveillance positron emission tomography scan detected a solitary lung metastasis, leading to a partial lobectomy and confirmation of further spread of the malignant melanoma.
恶性黑素瘤以前曾与副肿瘤综合征有关，包括皮肌炎。我们报告了一例涉及一名 34 岁女性的病例，该患者出现持续性颈部和上半身皮疹，临床表现提示皮肌炎。患者曾有右肩部病变病史，该病变之前已被切除；进一步的影像学检查发现孤立性腋窝淋巴结，活检结果与恶性黑素瘤一致。次年，监测正电子发射断层扫描（PET）发现孤立性肺转移，行部分肺叶切除术并证实恶性黑素瘤进一步扩散。
