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雄激素受体拮抗剂氟他胺治疗女性型脱发。

Treatment of female pattern hair loss with the androgen receptor antagonist flutamide.

机构信息

Department of Dermatology, St. Vincent's Hospital Melbourne and Department of Medicine, St. Vincent's Hospital, University of Melbourne, Melbourne, Victoria, Australia

出版信息

Australas J Dermatol. 2011 May;52(2):132-4. doi: 10.1111/j.1440-0960.2010.00735.x. Epub 2011 Mar 1.

Abstract

Female pattern hair loss is a common but difficult to manage condition. Commonly used treatments include oral antiandrogens such as spironolactone and topical minoxidil. The response to treatment is variable. We report a woman whose hair loss progressed while using spironolactone and topical minoxidil in combination, but reversed with flutamide, a potent androgen receptor antagonist.

摘要

女性型脱发是一种常见但难以治疗的疾病。常用的治疗方法包括口服抗雄激素药物,如螺内酯和外用米诺地尔。治疗反应因人而异。我们报告了一例女性患者,她在使用螺内酯和外用米诺地尔联合治疗时脱发进展,但改用强效雄激素受体拮抗剂氟他胺后脱发逆转。

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