VA Greater Los Angeles Healthcare System, Los Angeles, CA 90073, USA.
Schizophr Bull. 2011 Jul;37(4):700-8. doi: 10.1093/schbul/sbr051. Epub 2011 May 23.
Visual masking provides several key advantages for exploring the earliest stages of visual processing in schizophrenia: it allows for control over timing at the millisecond level, there are several well-supported theories of the underlying neurobiology of visual masking, and it is amenable to examination by electroencephalogram (EEG) and functional magnetic resonance imaging (fMRI). In this paper, we provide an overview of the visual masking impairment schizophrenia, including the relevant theoretical mechanisms for masking impairment. We will discuss its relationship to clinical symptoms, antipsychotic medications, diagnostic specificity, and presence in at-risk populations. As part of this overview, we will cover the neural correlates of visual masking based on recent findings from EEG and fMRI. Finally, we will suggest a possible mechanism that could explain the patterns of masking findings and other visual processing findings in schizophrenia.
它可以在毫秒级控制时间，有几个关于视觉掩蔽潜在神经生物学的理论得到了很好的支持，并且可以通过脑电图 (EEG) 和功能磁共振成像 (fMRI) 进行检查。在本文中，我们提供了精神分裂症视觉掩蔽障碍的概述，包括与掩蔽障碍相关的理论机制。我们将讨论其与临床症状、抗精神病药物、诊断特异性和高危人群的关系。作为该概述的一部分，我们将根据 EEG 和 fMRI 的最新发现，介绍视觉掩蔽的神经相关性。最后，我们将提出一种可能的机制来解释精神分裂症中掩蔽发现和其他视觉加工发现的模式。
