Dunn A J, Green E J, Isaacson R L
Science. 1979 Jan 19;203(4377):281-3. doi: 10.1126/science.216073.
Intact male rats exhibited more grooming in unfamiliar testing chambers than in their home cages. Hypophysectomized rats showed a much reduced increase in grooming in these testing chambers. Intraventricular injections of antiserum to adrenocorticotropic hormone to intact rats decreased the grooming usually observed in the novel situation, whereas a similar injection of control serum did not produce this effect. Peripheral injections of the antiserum did not affect grooming. Since intraventricularly injected adrenocorticotropic hormone induces excessive grooming, these results suggest that the increased grooming observed in the novel environment may be at least partly due to the release of this hormone directly into the cerebral ventricular system.
完整的雄性大鼠在陌生的测试箱中比在其笼舍中表现出更多的梳理行为。垂体切除的大鼠在这些测试箱中的梳理行为增加量显著减少。向完整大鼠脑室内注射促肾上腺皮质激素抗血清会减少在新环境中通常观察到的梳理行为，而注射类似的对照血清则不会产生这种效果。外周注射抗血清对梳理行为没有影响。由于脑室内注射促肾上腺皮质激素会诱发过度梳理，这些结果表明在新环境中观察到的梳理行为增加可能至少部分归因于这种激素直接释放到脑室系统中。
