Suppr超能文献

关于百日咳疫苗接种的争议(作者译)

[The controversy concerning whooping cough vaccination (author's transl)].

作者信息

Fourquet R

出版信息

Sem Hop. 1978;54(41-42):1296-1301.

PMID:216113
Abstract

The importance of the neurological complications of whooping cough vaccination has been greatly exaggerated. Their frequency may vary tenfold, depending on the authors. Most of the latter are mainly linked to age and are thus coincidences. Other etiologies may be responsible, as also may a receptive constitutional background, the vaccine then simply reveals a preexisting condition. Present whooping cough vaccines are efficacious as shown by the fall in morbidity curves and the large number of cases in unvaccinated subjects during epidemics. Whooping cough in infants remains a problem which can only be solved by vaccination. Primary vaccination should be carried out as early as possible, while strictly observing the contraindications. The poor absorption of whooping cough vaccines is in favour of their injection by the intramuscular route which is better tolerated. Other vaccines with less reaction and more immunogenic are being sought.

摘要

百日咳疫苗接种所致神经并发症的重要性被极大地夸大了。其发生率可能相差十倍,这取决于不同的作者。大多数情况主要与年龄相关,因此属于巧合。其他病因也可能起作用,同样,易感性体质背景也可能有影响,疫苗只是揭示了一种预先存在的状况。目前的百日咳疫苗是有效的,发病率曲线的下降以及疫情期间未接种疫苗者中大量病例的出现都证明了这一点。婴儿百日咳仍然是一个问题,只能通过接种疫苗来解决。应尽早进行初次接种,同时严格遵守禁忌证。百日咳疫苗吸收不佳,因此倾向于采用耐受性更好的肌肉注射途径。人们正在寻找反应更小、免疫原性更强的其他疫苗。

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验