Shahani B T, Day T J, Cros D, Khalil N, Kneebone C S
Clinical Neurophysiology Laboratories, Massachusetts General Hospital, Boston 02114.
Arch Neurol. 1990 Jun;47(6):659-64. doi: 10.1001/archneur.1990.00530060069021.
The diagnostic value of two simple tests of autonomic function, the RR interval variation and the sympathetic skin response, was evaluated relative to symptoms of dysautonomia in 53 patients with peripheral neuropathy. Of 22 patients with peripheral neuropathy and clinical dysautonomia, 15 showed abnormal results on both tests, and 7 had abnormal results on one test only. In none of the patients with dysautonomia were both tests' results normal. Conversely, all 15 patients with abnormal results of both sympathetic skin response and RR interval variation had symptoms of dysautonomia, while 7 of 15 patients with abnormalities limited to one test had such symptoms. No patient with normal results on both tests had clinical dysautonomia. These data indicate that RR interval variation and sympathetic skin response, both of which can easily be performed in the electromyography laboratory, are helpful in combination in the assessment of autonomic function in peripheral neuropathies.
在53例周围神经病患者中，相对于自主神经功能障碍症状，评估了两种简单的自主神经功能测试（RR间期变异和交感神经皮肤反应）的诊断价值。在22例患有周围神经病和临床自主神经功能障碍的患者中，15例两项测试结果均异常，7例仅一项测试结果异常。自主神经功能障碍患者中无一例两项测试结果均正常。相反，交感神经皮肤反应和RR间期变异两项结果均异常的所有15例患者均有自主神经功能障碍症状，而15例仅一项测试异常的患者中有7例有此类症状。两项测试结果均正常的患者无临床自主神经功能障碍。这些数据表明，RR间期变异和交感神经皮肤反应均可在肌电图实验室轻松进行，两者结合有助于评估周围神经病中的自主神经功能。
