从委内瑞拉梅里达采集的巴卡维斯米娅果实的精油成分及抗菌活性
Essential oil composition and antibacteral activity of Vismia baccifera fruits collected from Mérida, Venezuela.
作者信息
Rojas Janne, Buitrago Alexis, Rojas Luis, Morales Antonio, Lucena María, Baldovino Shirley
机构信息
Organic Biomolecular Research Group, Research Institute, Faculty of Pharmacy and Bioanalysis, University of Los Andes, Mérida, Venezuela.
出版信息
Nat Prod Commun. 2011 May;6(5):699-700.
The essential oil from the fruits of Vismia baccifera Triana & Planch. (Gutttiferae), collected in June 2009, was analyzed by GC/MS. A yield of 0.6% oil was obtained by hydrodistillation. Twenty-seven components were identified by comparison of their mass spectra with those in the Wiley GC-MS Library data base. The major components were trans-cadin-l1,4-diene (36.6%), cis-cadin-1,4-diene (18.8%) and beta-caryophyllene (11.9%). The essential oil showed a broad spectrum of antibacterial activity against the important human pathogenic Gram-positive and Gram-negative bacteria Staphylococcus aureus (ATCC 25923), Enterococcus faecalis (ATCC 29212), Escherichia coli (ATCC 25992), Pseudomonas aeruginosa (ATCC 27853) and Klebsiella pneumoniae (ATCC 23357) with MIC values ranging from 9 to 37 microg/mL.
2009年6月采集的巴豆叶下珠（金丝桃科）果实的精油，采用气相色谱/质谱联用仪（GC/MS）进行分析。通过水蒸馏法获得了0.6%的出油率。通过将其质谱图与Wiley GC-MS数据库中的质谱图进行比较，鉴定出了27种成分。主要成分是反式杜松-1,4-二烯（36.6%）、顺式杜松-1,4-二烯（18.8%）和β-石竹烯（11.9%）。该精油对重要的人类致病革兰氏阳性菌和革兰氏阴性菌金黄色葡萄球菌（ATCC 25923）、粪肠球菌（ATCC 29212）、大肠杆菌（ATCC 25992）、铜绿假单胞菌（ATCC 27853）和肺炎克雷伯菌（ATCC 23357）显示出广谱抗菌活性，最低抑菌浓度（MIC）值在9至37微克/毫升之间。
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