Department of Obstetrics & Gynecology, Sahlgrenska Academy at University of Gothenburg, Gothenburg, Sweden.
Acta Obstet Gynecol Scand. 2011 Sep;90(9):955-60. doi: 10.1111/j.1600-0412.2011.01194.x. Epub 2011 Jun 27.
Neuralgic pain caused by entrapment of peripheral nerves can be a difficult clinical problem. The objective of the present study was to assess pain and quality of life in women with pain secondary to ilioinguinal nerve entrapment.
In a controlled prospective crossover study, women with ilioinguinal nerve entrapment were randomly allocated to either medical treatment or surgical resection of the ilioinguinal nerve.
A university hospital.
19 women, 21-60 years of age with pelvic pain of more than 6 months' duration.
Visual analogue (VA) scales and psychological general well-being (PGWB) scales were used to validate pain and quality of life, respectively.
Improvements were found in the group randomly allocated to surgery, p < 0.008 for the VA scale and p < 0.0098 for the PGWB scale, respectively. Nine of 10 women discontinued the medical arm of treatment because of side effects and/or lack of effect. After being shifted over to surgery, similar improvements were noted (p < 0.0002 and p < 0.0043, respectively).
The positive results found here indicate that surgery is superior to medical treatment in ilioinguinal nerve entrapment of unknown cause as well as after previous surgery. More randomized trials from different centers with larger numbers of women are needed to confirm these results.
由外周神经嵌压引起的神经痛是一个临床难题。本研究旨在评估因髂腹股沟神经嵌压引起疼痛的女性的疼痛和生活质量。
在一项对照前瞻性交叉研究中，将髂腹股沟神经嵌压的女性患者随机分配至接受药物治疗或髂腹股沟神经切除术。
一所大学医院。
19 名年龄在 21-60 岁之间、患有骨盆疼痛超过 6 个月的女性。
使用视觉模拟量表（VA 量表）和心理一般健康量表（PGWB 量表）分别对疼痛和生活质量进行验证。
随机分配至手术组的患者在 VA 量表（p < 0.008）和 PGWB 量表（p < 0.0098）上均有改善。由于副作用和/或疗效不佳，10 名女性中有 9 名停止了药物治疗。转至手术组后，也观察到类似的改善（p < 0.0002 和 p < 0.0043）。
此处的阳性结果表明，对于原因不明的髂腹股沟神经嵌压以及先前手术后的患者，手术优于药物治疗。需要来自不同中心、纳入更多女性的更多随机试验来证实这些结果。
