Cardiovascular Research Laboratories, Texas Heart Institute at St. Luke's Episcopal Hospital, Houston, TX, USA.
Artif Organs. 2011 Jul;35(7):E161-3. doi: 10.1111/j.1525-1594.2011.01233.x. Epub 2011 May 25.
Although current continuous-flow total artificial hearts (CFTAHs) are much smaller than previous models, venous kinking may still occur after device implantation, especially in smaller animals. By inserting a self-expanding stent at the site of venous narrowing in a sheep model implanted with a CFTAH, we were able to restore the normal venous geometry and dramatically increase the CFTAH output. Because this percutaneous approach avoids the challenges associated with reoperation in these cases, it may be useful to other CFTAH investigators.
尽管目前的连续血流全人工心脏(CFTAH)比以前的模型小得多,但在设备植入后,静脉仍然可能发生扭曲,尤其是在较小的动物中。通过在植入 CFTAH 的绵羊模型中静脉狭窄部位插入自扩张支架,我们能够恢复正常的静脉几何形状,并显著提高 CFTAH 的输出。由于这种经皮方法避免了在这些情况下与再次手术相关的挑战,因此它可能对其他 CFTAH 研究人员有用。