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纤维肌痛综合征中年女性睡眠质量的决定因素。

Determinants of sleep quality in middle-aged women with fibromyalgia syndrome.

机构信息

Section of Physical Education and Sports, University Pablo de Olavide, Carretera de Utrera, Km. 1 s ⁄ n, Seville, Spain.

出版信息

J Sleep Res. 2012 Feb;21(1):73-9. doi: 10.1111/j.1365-2869.2011.00929.x. Epub 2011 May 26.

DOI:10.1111/j.1365-2869.2011.00929.x
PMID:21615580
Abstract

The objectives of this study were: (i) to compare the sleep quality at home of patients with fibromyalgia with that of healthy controls; and (ii) to examine the factors associated with sleep quality in patients with fibromyalgia. In addition to anthropometric measures, 75 women with fibromyalgia and 48 healthy controls completed standardized questionnaires that assessed sleep quality, functional impairment (Fibromyalgia Impact Questionnaire), depression, anxiety and physical activity level. Comparisons between groups, correlation coefficients and a series of hierarchical multiple regressions were performed. The global Pittsburgh Sleep Quality Index scores were worse in patients with fibromyalgia than in the controls. This result was partly explained by the Fibromyalgia Impact Questionnaire score. For the patients with fibromyalgia, the results of the first model that tested the importance of demographic factors were not statistically significant. In the disease-related model, the duration of symptoms and symptom severity contributed to poor sleep quality. A measurement of physical activity participation and the sum of the skinfold thickness were added to the demographic factors. In the psychological model, the level of anxiety contributed to poor sleep quality. When all variables were entered simultaneously, the level of physical activity, duration of symptoms and symptom severity remained significant determinants of sleep quality. In conclusion, our results showed that the symptoms associated with fibromyalgia contributed to poor overall sleep quality in patients compared with healthy subjects. The findings also suggest that the duration of symptoms, symptom severity and especially a sedentary lifestyle contributed to decreased sleep quality in patients with fibromyalgia.

摘要

本研究的目的是

(i)比较纤维肌痛患者在家中的睡眠质量与健康对照组的睡眠质量;(ii)探讨纤维肌痛患者睡眠质量的相关因素。除了人体测量学指标外,75 名纤维肌痛患者和 48 名健康对照者完成了标准化问卷,评估了睡眠质量、功能障碍(纤维肌痛影响问卷)、抑郁、焦虑和身体活动水平。对两组进行了比较,计算了相关系数,并进行了一系列分层多元回归分析。纤维肌痛患者的匹兹堡睡眠质量指数总评分较对照组差。这一结果部分可以用纤维肌痛影响问卷评分来解释。对于纤维肌痛患者,测试人口统计学因素重要性的第一个模型的结果没有统计学意义。在与疾病相关的模型中,症状持续时间和症状严重程度与睡眠质量差有关。将身体活动参与的测量值和皮肤褶皱厚度的总和添加到人口统计学因素中。在心理模型中,焦虑水平与睡眠质量差有关。当所有变量同时输入时,身体活动水平、症状持续时间和症状严重程度仍然是睡眠质量的重要决定因素。总之,我们的研究结果表明,与健康受试者相比,纤维肌痛相关的症状导致患者整体睡眠质量较差。研究结果还表明,症状持续时间、症状严重程度,尤其是久坐不动的生活方式,与纤维肌痛患者睡眠质量下降有关。

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