Ferrari M, Losio M N, Gualandi G L, Bugnetti M
Istituto Zooprofilattico Sperimentale della Lombardia e dell'Emilia, Brescia, Italy.
Microbiologica. 1990 Apr;13(2):161-3.
When BHK21 cells were grown according to the microcarrier's system, they reached the highest concentration in 72 hrs. The infectivity of Foot-and-Mouth Disease (FMD) virus in BHK21 microcarrier culture increased 10 times compared with the conventional monolayer culture in rolling bottles.