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一名12岁女孩的无排卵性出血作为罕见未分化肉瘤的首发症状。

Anovulatory bleeding in a 12-year-old as presenting sign for rare undifferentiated sarcoma.

作者信息

Arbuckle Janeen, Hoover Kim

机构信息

Division of Women's Reproductive Healthcare, Department of Obsterics and Gynecology, University of Alabama at Birmingham, Birmingham, AL 35249, USA.

出版信息

J Pediatr Adolesc Gynecol. 2011 Aug;24(4):e97-e100. doi: 10.1016/j.jpag.2011.03.006. Epub 2011 May 28.

Abstract

BACKGROUND

Abnormal uterine bleeding is a common phenomenon in perimenarchal females. Though most cases of abnormal bleeding are due to anovulatory bleeding or bleeding disorders, rare cases are attributable to underlying malignancy.

CASE

Here we report a 12-year-old female patient who presented with abnormal uterine bleeding three months after menarche. She was ultimately diagnosed with a pelvic sarcoma of unknown primary origin. She was subsequently treated with chemotherapy, whole pelvic radiation, and hysterectomy with bilateral salpingo-oophorectomy.

SUMMARY

Abnormal uterine bleeding unresponsive to conventional temporizing measures should be thoroughly evaluated. Management of pelvic malignancies in the pediatric population requires cooperation amongst specialists from an array of disciplines.

摘要

背景

青春期前女性子宫异常出血是一种常见现象。虽然大多数异常出血病例是由于无排卵性出血或出血性疾病,但罕见病例可归因于潜在的恶性肿瘤。

病例

在此,我们报告一名12岁女性患者,她在初潮后三个月出现子宫异常出血。她最终被诊断为原发灶不明的盆腔肉瘤。随后她接受了化疗、全盆腔放疗以及子宫切除术加双侧输卵管卵巢切除术。

总结

对常规临时措施无反应的子宫异常出血应进行全面评估。儿科人群盆腔恶性肿瘤的治疗需要多学科专家的合作。

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