Division of Maternal Fetal Medicine, Department of Obstetrics and Gynecology, University of Cincinnati College of Medicine, Cincinnati, OH 45267-0526, USA.
Am J Obstet Gynecol. 2011 Aug;205(2):128.e1-7. doi: 10.1016/j.ajog.2011.03.051. Epub 2011 Apr 8.
The purpose of this study was to quantify the relationship between class of obesity and rate of failed induction of labor.
Using the Ohio Department of Health's birth certificate database from January 1, 2006, through December 31, 2007, we performed a population-based cohort study that compared failed induction of labor rates between obese and normal-weight women.
The rate of induction is associated with increasing body mass index from 28% in normal-weight women to 34% in class III obese women (body mass index, ≥40 kg/m2). Induction failure rates are also associated with increasing obesity class from 13% in normal-weight women to 29% in class III obese women. Women with class III obesity without a previous vaginal delivery and a macrosomic fetus had the highest rate of failed induction at 80%.
Obesity is associated with an increased risk of failed labor induction that appears to be related directly to increasing class of obesity.
本研究旨在量化肥胖程度与引产失败率之间的关系。
利用俄亥俄州卫生部门 2006 年 1 月 1 日至 2007 年 12 月 31 日的出生证明数据库,我们进行了一项基于人群的队列研究,比较了肥胖和正常体重女性的引产失败率。
随着体重指数从正常体重女性的 28%增加到 III 级肥胖女性(体重指数≥40kg/m2)的 34%,引产率与体重指数呈正相关。引产失败率也与肥胖程度的增加有关,从正常体重女性的 13%增加到 III 级肥胖女性的 29%。无阴道分娩史和胎儿巨大的 III 级肥胖女性引产失败率最高,达 80%。
肥胖与引产失败的风险增加有关,这似乎与肥胖程度的增加直接相关。