Department of Neonatal Paediatrics, University Hospital of North Tees, Stockton, UK.
Semin Fetal Neonatal Med. 2011 Oct;16(5):275-8. doi: 10.1016/j.siny.2011.04.007. Epub 2011 May 28.
Non-invasive respiratory support techniques such as continuous positive airway pressure (CPAP) have been increasingly used for management of surfactant-deficient lung disease in preterm infants. The successful use of this approach depends upon the condition of the baby at birth and requires the establishment of spontaneous breathing at birth. The reported advantages of CPAP in observational studies demonstrating a reduction in chronic lung disease have not been substantiated in recently reported well-designed randomised trials. This approach is now more established in larger and more mature preterm infants, and proper patient selection with close observation should be exercised when used in extremely low gestational age infants.
非侵入性呼吸支持技术，如持续气道正压通气（CPAP），已越来越多地用于治疗早产儿肺表面活性物质缺乏症。这种方法的成功应用取决于婴儿出生时的状况，并需要在出生时建立自主呼吸。在观察性研究中，CPAP 的应用已被证明可以降低慢性肺部疾病的发生率，但在最近报道的精心设计的随机试验中并未得到证实。这种方法在更大、更成熟的早产儿中应用更为广泛，在极低胎龄儿中应用时应进行适当的患者选择和密切观察。
