Wolgin D L, Wade J V
Institute for the Study of Alcohol and Drug Dependence, Florida Atlantic University, Boca Raton 33431-0991.
Behav Neurosci. 1990 Jun;104(3):438-40. doi: 10.1037//0735-7044.104.3.438.
The effect of lithium chloride-induced conditioned taste aversions on appetitive and consummatory behavior was determined. Rats were given access to a 0.1% saccharin solution for 15 min either in bottles or by infusion through an intraoral cannula. Bottle-fed rats given postprandial injections of lithium chloride showed greater aversion to saccharin than cannula-fed rats. During extinction, cannula-fed rats gradually recovered to control levels of intake, whereas bottle-fed rats continued to avoid the saccharin. These results suggest that lithium chloride affects appetitive behavior to a greater extent than it affects consummatory behavior.
测定了氯化锂诱导的条件性味觉厌恶对食欲和进食行为的影响。大鼠通过瓶子或经口腔内插管输注,给予0.1%的糖精溶液15分钟。餐后注射氯化锂的瓶饲大鼠比插管饲大鼠对糖精的厌恶程度更高。在消退期,插管饲大鼠的摄入量逐渐恢复到对照水平,而瓶饲大鼠继续回避糖精。这些结果表明,氯化锂对食欲行为的影响比对进食行为的影响更大。