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大鼠和小鼠梳理过程中条件性味觉厌恶形成与新物恐惧症之间的差异。

Disparity between formation of conditioned flavor aversions and neophobia during grooming in rats and mice.

作者信息

Stewart C N, Reidinger R F

出版信息

Physiol Behav. 1984 Jun;32(6):955-9. doi: 10.1016/0031-9384(84)90285-3.

DOI:10.1016/0031-9384(84)90285-3
PMID:6093167
Abstract

Mice (Mus musculus) allowed to groom a paste containing saccharin from their fur before injection with lithium chloride displayed a saccharin aversion in subsequent drinking preference tests. No attenuation of neophobia was observed in mice grooming saccharin because the animals failed to display a neophobia towards saccharin in drinking tests. Rattus norvegicus displayed neophobia towards saccharin in two- and single-bottle drinking tests but this neophobia was not attenuated by grooming experience with the saccharin paste. Rats apparently learn that if a taste is hazardous in the grooming context it is also likely hazardous in an appetitive context. Learned safety in grooming, however, does not generalize into the appetitive context. The results support the view that neophobia and learned taste aversion depend upon different mechanisms.

摘要

在注射氯化锂之前,允许小鼠(小家鼠)从其皮毛上梳理含有糖精的糊剂,这些小鼠在随后的饮水偏好测试中表现出对糖精的厌恶。在梳理糖精的小鼠中未观察到新物恐惧症的减轻,因为这些动物在饮水测试中未表现出对糖精的新物恐惧症。褐家鼠在双瓶和单瓶饮水测试中表现出对糖精的新物恐惧症,但这种新物恐惧症并未因用糖精糊剂的梳理经历而减轻。大鼠显然了解到,如果一种味道在梳理情境中是有害的,那么在进食情境中也可能是有害的。然而,在梳理中习得的安全性并不会推广到进食情境中。这些结果支持了新物恐惧症和习得性味觉厌恶依赖于不同机制的观点。

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Disparity between formation of conditioned flavor aversions and neophobia during grooming in rats and mice.大鼠和小鼠梳理过程中条件性味觉厌恶形成与新物恐惧症之间的差异。
Physiol Behav. 1984 Jun;32(6):955-9. doi: 10.1016/0031-9384(84)90285-3.
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[Comparative effects of lesion of the basolateral nucleus and lateral nucleus of the amygdaloid body on neophobia and conditioned taste aversion in the rat].[杏仁体基底外侧核与外侧核损伤对大鼠新物恐惧症和条件性味觉厌恶的比较影响]
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