Meachum C L, Bernstein I L
Department of Psychology, University of Washington, Seattle 98195.
Behav Neurosci. 1990 Oct;104(5):711-5. doi: 10.1037//0735-7044.104.5.711.
The present experiments examined whether behavioral conditioned responses (CRs) develop to lithium chloride (LiCl)-paired tastes and whether these CRs are similar to the behaviors that follow administration of the drug. Rats were exposed to a saccharin solution via intraoral infusions before being injected with either LiCl or saline. CRs were assessed after conditioning when the saccharin conditioned stimulus was delivered alone. The unconditioned response to LiCl delivery is a very distinctive posture that has been termed "lying-on-belly." The present study indicates that this behavior pattern also occurs after the delivery of a LiCl-paired taste solution. The similarity between these unconditioned and conditioned behaviors is consistent with the hypothesis that responses are conditioned during taste aversion acquisition and that CRs are similar to those that are generated by the drugs used in conditioning.
本实验研究了对与氯化锂（LiCl）配对的味道是否会产生行为条件反应（CRs），以及这些CRs是否与给药后出现的行为相似。在给大鼠注射LiCl或生理盐水之前，通过口腔内灌注使其接触糖精溶液。在条件化后，当单独呈现糖精条件刺激时评估CRs。对LiCl给药的无条件反应是一种非常独特的姿势，被称为“腹部着地躺卧”。本研究表明，在给予与LiCl配对的味觉溶液后也会出现这种行为模式。这些无条件行为和条件行为之间的相似性与以下假设一致：在味觉厌恶习得过程中反应被条件化，并且CRs与条件化中使用的药物所产生的反应相似。
