Division of Nuclear Medicine and Molecular Imaging, Children's Hospital Boston and Harvard Medical School, Boston, Massachusetts 02115, USA.
J Nucl Med. 2011 Jun;52(6):905-25. doi: 10.2967/jnumed.110.084202.
Nuclear medicine has an important role in the care of newborns and children less than 1 y old. Patients in this age group present with a spectrum of diseases different from those of older children or adults. These patients can benefit from the full range of nuclear medicine studies. In these young children, nuclear medicine studies are more likely to be used to evaluate a wide range of congenital conditions but also can be helpful for evaluating acquired conditions such as infection, cancer, and trauma. This review first will cover the general aspects of nuclear medicine practice with these patients, including the special considerations that can help achieve successful diagnostic imaging. These topics will include clinical indications, imaging technology, instrumentation, software, positioning and immobilization, sedation, local and general anesthesia, radiopharmaceutical doses, radiation risk, and dose reduction. The review then will discuss the specific nuclear medicine studies that typically are obtained in patients in this age group. With extra care and attention to the special needs of this population, nuclear medicine departments can successfully study patients less than 1 y old.
核医学在新生儿和 1 岁以下儿童的护理中具有重要作用。该年龄段的患者所患疾病与年龄较大的儿童或成人不同。这些患者可以从核医学研究的各个方面受益。在这些幼儿中,核医学研究更有可能用于评估广泛的先天性疾病,但也有助于评估获得性疾病,如感染、癌症和创伤。本综述首先将涵盖核医学在这些患者中的一般实践方面,包括有助于实现成功诊断成像的特殊考虑因素。这些主题将包括临床适应证、成像技术、仪器、软件、定位和固定、镇静、局部和全身麻醉、放射性药物剂量、辐射风险和剂量减少。然后,该综述将讨论通常在该年龄段患者中获得的特定核医学研究。通过对该人群特殊需求的额外关注和重视,核医学部门可以成功地对 1 岁以下的患者进行研究。