支气管源性癌所致纵隔压迫的处理

Management of mediastinal compression due to bronchogenic carcinoma.

作者信息

Anand A K, Ayyagari S, Sharma S C, Patel F D, Gupta B D

出版信息

Acta Radiol Oncol. 1985 May-Jun;24(3):233-5. doi: 10.3109/02841868509134392.

Abstract

Fifty-six cases of bronchogenic carcinoma with mediastinal compression were analyzed retrospectively. Microscopic confirmation was obtained in 23 patients and small cell carcinoma was most frequent. Radiation treatment gave complete remission in about 70 per cent when the total tumour dose exceeded 35 Gy fractionated during 3 weeks. Addition of cyclophosphamide marginally increased the remission rate to about 85 per cent. Total tumour doses of less than 35 Gy gave obviously poorer results. The response rate was highest in small cell carcinoma.

摘要

对56例伴有纵隔压迫的支气管源性癌患者进行了回顾性分析。23例患者获得了显微镜确诊，其中小细胞癌最为常见。当肿瘤总剂量在3周内分阶段超过35 Gy时，放射治疗使约70%的患者完全缓解。加用环磷酰胺使缓解率略有提高，达到约85%。肿瘤总剂量小于35 Gy时，结果明显较差。小细胞癌的缓解率最高。