Department of Dermatology, University Hospital, Zurich, Switzerland.
Dermatology. 2011;223(1):1-3. doi: 10.1159/000328136. Epub 2011 May 27.
We report on a 15-year-old female with a 3-month history of a pruritic, erythematous cutaneous eruption on the right cheek and perioral area. The lesion had a linear distribution following the lines of Blaschko. Histopathological findings and direct immunofluorescence were compatible with chronic cutaneous lupus erythematosus (LE). Treatment with topical steroids and systemic antimalarial agents over 2 months showed hardly any improvement contrary to similar cases reported in the literature in the past. Histological findings move this case close to LE. However, the unusual clinical presentation as well as the resistance to antimalarial drugs do not fully allow to confirm this suspicion. Therefore, we recommend to call this new entity LE-like facial Blaschkitis of the adult.
我们报告了一例 15 岁女性，右侧脸颊和口周区域出现瘙痒、红斑性皮疹，病史 3 个月。皮损呈线状分布，沿 Blaschko 线分布。组织病理学发现和直接免疫荧光检查符合慢性皮肤红斑狼疮（LE）。2 个月的局部类固醇和全身抗疟药物治疗几乎没有改善，与过去文献中报道的类似病例相反。组织学发现使该病例接近 LE。然而，不寻常的临床表现以及对抗疟药物的耐药性不能完全证实这种怀疑。因此，我们建议将这种新实体称为成人类似 LE 的面部 Blaschkitis。
