Nico M M S, Bologna S B, Lourenço S V
Department of Dermatology, Medical School, University of São Paulo, São Paulo, Brazil.
Clin Exp Dermatol. 2014 Jul;39(5):563-9. doi: 10.1111/ced.12368.
Lupus erythematosus (LE) frequently compromises the skin, lips and oral mucosa. There is a large body of medical and dental literature about the cutaneous and mucosal lesions of LE, but very little has been written specifically about labial lupus. The lip has a peculiar anatomical and histological architecture, and LE lesions at this site may have some distinct features. This article reviews the existing data and adds some new concepts to the issue of labial lupus in all of its presentations, comparing such lesions to the well-established characterization of cutaneous LE (in acute, subacute and chronic lesions), and highlighting some special clinical features that may enable a better diagnosis and differential diagnosis of lip diseases.
红斑狼疮（LE）常累及皮肤、唇部和口腔黏膜。关于LE的皮肤和黏膜病变，有大量的医学和牙科文献，但专门针对唇部狼疮的论述却很少。唇部具有独特的解剖和组织学结构，该部位的LE病变可能具有一些明显特征。本文回顾了现有数据，并为唇部狼疮的各种表现形式增添了一些新观念，将此类病变与已明确的皮肤LE特征（急性、亚急性和慢性病变）进行比较，并突出一些有助于更好地诊断和鉴别唇部疾病的特殊临床特征。
