急性胰腺炎：急性戊型肝炎的罕见并发症。

Acute pancreatitis: a rare complication of acute hepatitis E.

机构信息

Service de Pathologie Infectieuse et Tropicale, Hôpital d'Instruction des Armées Laveran, Marseille, France.

出版信息

J Clin Virol. 2011 Jul;51(3):202-4. doi: 10.1016/j.jcv.2011.04.009. Epub 2011 May 31.

DOI:10.1016/j.jcv.2011.04.009

Abstract

Hepatitis E is an emerging imported disease in Europa but autochthonous cases are described for some years. Extra-hepatic associated manifestations are published. We report a case of acute necrotizing pancreatitis associated with imported acute viral E hepatitis (genotype 1a) in a 26 years old French man travelling and originated from Pakistan. The outcome is favourable spontaneously in two months. This life-threatening hepatitis E related complication is unknown in Europa where genotype 3 virus strains prevail. The clinical presentation is stereotyped with the onset of pancreatitis in the second or third weeks of hepatitis evolution in an Indian male in his second or third decade infected with genotype 1 strain. No pancreatitis-related death is reported in the 13 previous reported cases.

摘要

戊型肝炎在欧洲是一种新出现的输入性疾病，但已有多年的本地发病病例报告。也有报道称存在肝外相关表现。我们报告了一例 26 岁的法国男性病例，他从巴基斯坦旅行归来后感染了 1a 型急性戊型肝炎病毒，并发急性坏死性胰腺炎。两个月后，病情自然好转。在欧洲，基因型 3 病毒株占主导地位，这种与戊型肝炎相关的危及生命的并发症尚属未知。临床表现具有一定特征性，在感染 1 型病毒株的印度男性中，在肝炎发病的第二或第三周出现胰腺炎，在其第二或第三个十年。在之前报告的 13 例病例中，没有与胰腺炎相关的死亡病例。