[牛初乳中的免疫球蛋白成分及抗病毒活性]

[Immunoglobulin components and anti-viral activities in bovine colostrum].

作者信息

Ushijima H, Dairaku M, Honnma H, Mukoyama A, Kitamura T

机构信息

Department of Enteroviruses, National Institute of Health, Japan.

出版信息

Kansenshogaku Zasshi. 1990 Mar;64(3):274-9. doi: 10.11150/kansenshogakuzasshi1970.64.274.

DOI:10.11150/kansenshogakuzasshi1970.64.274

PMID:2162896

Abstract

Bovine colostrum whey and immunoglobulins were prepared. Their characteristics and anti-viral activities were studied:IgG, IgA and IgM were found in bovine colostrum. Most IgG was polymerized. Although neutralization activities against bovine, simian and human rotaviruses existed, anti-human adenovirus antibody was not found. Effects on prophylaxis and treatment for rotavirus gastroenteritis were expected.

摘要

制备了牛初乳乳清和免疫球蛋白。研究了它们的特性和抗病毒活性：在牛初乳中发现了IgG、IgA和IgM。大多数IgG是聚合的。虽然存在针对牛、猴和人轮状病毒的中和活性，但未发现抗人腺病毒抗体。期望其对轮状病毒胃肠炎的预防和治疗有效果。