Wells P W, Snodgrass D R, Herring J A, Dawson A M
Vet Rec. 1978 Jul 15;103(3):46-8. doi: 10.1136/vr.103.3.46.
Ewes were vaccinated two to three weeks prior to mating with a formalin-treated preparation of lamb rotavirus. The colostrum and milk produced by vaccinated ewes after the subsequent pregnancy were shown to contain significantly higher titres of antibody to the virus than did mammary secretions from non-vaccinates. The virus neutralising antibody activity was associated with IgG in both colostrum and milk. However, IgG concentrations in the mammary secretions of vaccinates and non-vaccinates did not differ. It is suggested that vaccination of the dam may be of value in protecting the suckled neonatal lamb against rotavirus infection.
在母羊配种前两到三周，用经福尔马林处理的羔羊轮状病毒制剂对其进行接种。结果显示，接种后的母羊在随后怀孕后所产生的初乳和乳汁中，病毒抗体滴度显著高于未接种母羊的乳腺分泌物。初乳和乳汁中的病毒中和抗体活性均与IgG相关。然而，接种母羊和未接种母羊的乳腺分泌物中IgG浓度并无差异。研究表明，给母羊接种疫苗可能对保护哺乳新生羔羊免受轮状病毒感染具有重要意义。
