Honzumi M, Miura T, Fujino I, Suzuki H
Second Department of Surgery, Mie University School of Medicine, Tsu, Japan.
Jpn J Surg. 1990 May;20(3):331-4. doi: 10.1007/BF02470669.
A female infant who presented with abdominal distention and jaundice at the age of 2 days underwent resection of a large hepatoblastoma at the age of 8 days by a right trisegmentectomy. Although postoperative adjuvant chemotherapy was not given, the patient is now alive without disease 10 months after surgery. We were able to find only 10 other cases of hepatoblastoma occurring in the newborn period in the Japanese literature. Resection of the tumor was performed in seven of these patients, of whom there were five survivors, one operative death and one death due to tumor recurrence. However, none of the three patients treated conservatively survived. Thus, we suggest that in newborns with hepatoblastoma, resection of the tumor should be performed, if feasible, but believe that postoperative chemotherapy is not necessary for patients whose tumor has been completely resected.
一名2日龄出现腹胀和黄疸的女婴在8日龄时接受了右三叶切除术，切除了一个巨大的肝母细胞瘤。尽管术后未进行辅助化疗，但患者术后10个月仍无病存活。在日本文献中，我们仅能找到另外10例新生儿期发生的肝母细胞瘤病例。其中7例患者进行了肿瘤切除术，其中5例存活，1例手术死亡，1例因肿瘤复发死亡。然而，3例保守治疗的患者均未存活。因此，我们建议对于患有肝母细胞瘤的新生儿，若可行应进行肿瘤切除术，但我们认为对于肿瘤已完全切除的患者术后无需化疗。
