Ogita S, Tokiwa K, Takahashi T, Imashuku S, Sawada T
Jpn J Surg. 1987 Jan;17(1):21-7. doi: 10.1007/BF02470580.
Combination chemotherapy (adriamycin, vincristine, cyclophosphamide, etc.) was prescribed for two patients with initially unresectable hepatoblastoma. A significant reduction in tumor size occurred, and subsequent successful resection was feasible in one, although in the other the regressed tumor remained inoperable due to the link to the hepatic veins. The survival time for these patients was 9 months after operation and 41 months from diagnosis, respectively. Preoperative combination chemotherapy for initially unresectable hepatoblastoma facilitates surgical removal under more favorable conditions of a decreased tumor size.
对两名最初无法切除的肝母细胞瘤患者采用联合化疗（阿霉素、长春新碱、环磷酰胺等）。两名患者的肿瘤大小均显著缩小，其中一名随后成功进行了切除，不过另一名患者因肿瘤与肝静脉相连，缩小后的肿瘤仍无法切除。这两名患者术后的存活时间分别为9个月和从诊断起41个月。对于最初无法切除的肝母细胞瘤，术前联合化疗有助于在肿瘤体积减小这一更有利的条件下进行手术切除。
