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DNA 模板化整体用于无标记和实时荧光开启检测单链 DNA 的酶切/氧化切割。

DNA-templated ensemble for label-free and real-time fluorescence turn-on detection of enzymatic/oxidative cleavage of single-stranded DNA.

机构信息

State Key Laboratory of Rare Earth Resources Utilization, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, Changchun, 130022, China.

出版信息

Chem Commun (Camb). 2011 Jul 28;47(28):8133-5. doi: 10.1039/c1cc12216a. Epub 2011 May 31.

DOI:10.1039/c1cc12216a
PMID:21629944
Abstract

We have demonstrated a DNA-templated small molecule ensemble that allows the label-free fluorescence turn-on detection of enzymatic or oxidative cleavage of single-stranded DNA with high sensitivity and selectivity.

摘要

我们已经证明了一种 DNA 模板化小分子集合体,它可以实现无标记荧光开启检测,对单链 DNA 的酶切或氧化切割具有高灵敏度和选择性。

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