TU Dortmund, Germany.
Nat Prod Rep. 2011 Jul;28(7):1203-7. doi: 10.1039/c1np00030f. Epub 2011 Jun 1.
The prospect of endophytes capable of producing associated plant natural products with therapeutic potential is undeniable. However, the unyielding struggle so far to transform these potential sources into sustainable microbial manufacturers on a commercial scale has been disappointing. In this Viewpoint, we address this trade-off between endophyte discovery and viable industrial application.
具有产生具有治疗潜力的植物天然产物的内生菌的前景是不可否认的。然而，迄今为止，将这些潜在的资源转化为具有商业规模的可持续微生物制造商的不屈不挠的斗争一直令人失望。在本观点中，我们解决了内生菌发现和可行的工业应用之间的这种权衡。
