Morris D J
Department of Pathological Sciences, University of Manchester Medical School, United Kingdom.
Rev Infect Dis. 1990 May-Jun;12(3):557-9. doi: 10.1093/clinids/12.3.557.
In the absence of proof that cytomegalovirus is the cause of colitis and retinitis in human immunodeficiency virus (HIV)-infected patients, it is proposed that HIV plays a direct role in the causation of these diseases. Clinical and epidemiologic evidence is cited to support this hypothesis. A direct role for HIV in the etiology of retinitis and colitis in HIV-infected patients could have important implications for antiviral chemotherapy in these diseases.
在缺乏证据证明巨细胞病毒是人类免疫缺陷病毒(HIV)感染患者中结肠炎和视网膜炎病因的情况下,有人提出HIV在这些疾病的病因中起直接作用。文中引用了临床和流行病学证据来支持这一假说。HIV在HIV感染患者视网膜炎和结肠炎病因中所起的直接作用可能对这些疾病的抗病毒化疗具有重要意义。