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在感染人类免疫缺陷病毒(HIV)的患者中,视网膜炎和结肠炎的病因是HIV而非巨细胞病毒吗?

Is human immunodeficiency virus (HIV) rather than cytomegalovirus the cause of retinitis and colitis in HIV-infected patients?

作者信息

Morris D J

机构信息

Department of Pathological Sciences, University of Manchester Medical School, United Kingdom.

出版信息

Rev Infect Dis. 1990 May-Jun;12(3):557-9. doi: 10.1093/clinids/12.3.557.

DOI:10.1093/clinids/12.3.557
PMID:2163096
Abstract

In the absence of proof that cytomegalovirus is the cause of colitis and retinitis in human immunodeficiency virus (HIV)-infected patients, it is proposed that HIV plays a direct role in the causation of these diseases. Clinical and epidemiologic evidence is cited to support this hypothesis. A direct role for HIV in the etiology of retinitis and colitis in HIV-infected patients could have important implications for antiviral chemotherapy in these diseases.

摘要

在缺乏证据证明巨细胞病毒是人类免疫缺陷病毒(HIV)感染患者中结肠炎和视网膜炎病因的情况下,有人提出HIV在这些疾病的病因中起直接作用。文中引用了临床和流行病学证据来支持这一假说。HIV在HIV感染患者视网膜炎和结肠炎病因中所起的直接作用可能对这些疾病的抗病毒化疗具有重要意义。

相似文献

1
Is human immunodeficiency virus (HIV) rather than cytomegalovirus the cause of retinitis and colitis in HIV-infected patients?在感染人类免疫缺陷病毒(HIV)的患者中,视网膜炎和结肠炎的病因是HIV而非巨细胞病毒吗?
Rev Infect Dis. 1990 May-Jun;12(3):557-9. doi: 10.1093/clinids/12.3.557.
2
Cytomegalovirus in the setting of infection with human immunodeficiency virus.人类免疫缺陷病毒感染背景下的巨细胞病毒
Rev Infect Dis. 1990 Sep-Oct;12 Suppl 7:S811-9. doi: 10.1093/clinids/12.supplement_7.s811.
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Treatment of aggressive cytomegalovirus retinitis with ganciclovir in combination with foscarnet in a child infected with human immunodeficiency virus.在一名感染人类免疫缺陷病毒的儿童中,使用更昔洛韦联合膦甲酸钠治疗侵袭性巨细胞病毒性视网膜炎。
J Pediatr. 1992 Mar;120(3):483-6. doi: 10.1016/s0022-3476(05)80926-6.
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Diagnosis of human cytomegalovirus-induced retinitis in human immunodeficiency virus type 1-infected subjects by using the polymerase chain reaction.利用聚合酶链反应诊断1型人类免疫缺陷病毒感染受试者中的人巨细胞病毒诱导的视网膜炎
J Clin Microbiol. 1991 Nov;29(11):2621-2. doi: 10.1128/jcm.29.11.2621-2622.1991.
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Overview of cytomegalovirus infections in HIV-infected patients: current therapies and future strategies.
J Acquir Immune Defic Syndr (1988). 1991;4 Suppl 1:S1-5.
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Risk for retinitis in patients with AIDS can be assessed by quantitation of threshold levels of cytomegalovirus DNA burden in blood.艾滋病患者发生视网膜炎的风险可通过对血液中巨细胞病毒DNA载量阈值水平进行定量分析来评估。
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Cytomegalovirus as a possible cofactor in HIV disease progression.巨细胞病毒作为人类免疫缺陷病毒疾病进展的一种可能辅助因素。
J Acquir Immune Defic Syndr (1988). 1991;4 Suppl 1:S47-52.
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[Clinical manifestations and course of cytomegalovirus colitis in AIDS patients].[艾滋病患者巨细胞病毒性结肠炎的临床表现及病程]
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引用本文的文献

1
Antiviral chemotherapy for retinitis in HIV-infected patients.针对感染HIV患者视网膜炎的抗病毒化疗。
Genitourin Med. 1991 Feb;67(1):72-3. doi: 10.1136/sti.67.1.72.
2
Cytomegalovirus ileitis presenting as massive rectal bleeding in infancy.巨细胞病毒性回肠炎表现为婴儿期大量直肠出血。
Arch Dis Child. 1991 Jul;66(7):883-4. doi: 10.1136/adc.66.7.883.