利用聚合酶链反应诊断1型人类免疫缺陷病毒感染受试者中的人巨细胞病毒诱导的视网膜炎
Diagnosis of human cytomegalovirus-induced retinitis in human immunodeficiency virus type 1-infected subjects by using the polymerase chain reaction.
作者信息
Fenner T E, Garweg J, Hufert F T, Boehnke M, Schmitz H
机构信息
Department of Virology, Bernhard Nocht Institute for Tropical Medicine, Hamburg, Germany.
出版信息
J Clin Microbiol. 1991 Nov;29(11):2621-2. doi: 10.1128/jcm.29.11.2621-2622.1991.
Abstract
In 13 of 16 AIDS patients with retinitis, a herpesviruslike infection was diagnosed by clinical investigation. In 12 of the 13 patients, human cytomegalovirus (HCMV) DNA was detected in 5 microliters of aqueous humor by using the polymerase chain reaction (PCR). In the aqueous humor of 12 control patients HCMV DNA could not be detected by PCR. PCR may be used to monitor specific antiviral long-term therapy in HCMV retinitis.
摘要
在16例患有视网膜炎的艾滋病患者中，有13例经临床检查诊断为疱疹病毒样感染。在这13例患者中的12例中，通过聚合酶链反应（PCR）在5微升房水中检测到了人巨细胞病毒（HCMV）DNA。在12例对照患者的房水中，通过PCR未检测到HCMV DNA。PCR可用于监测HCMV视网膜炎的特异性抗病毒长期治疗。
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Diagnosis of human cytomegalovirus-induced retinitis in human immunodeficiency virus type 1-infected subjects by using the polymerase chain reaction.利用聚合酶链反应诊断1型人类免疫缺陷病毒感染受试者中的人巨细胞病毒诱导的视网膜炎
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本文引用的文献
1
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J Infect Dis. 1982 Feb;145(2):191-9. doi: 10.1093/infdis/145.2.191.
2
Herpesvirus infections (cytomegalovirus, herpes simplex virus, varicella-zoster virus). How to use ganciclovir (DHPG) and acyclovir.疱疹病毒感染（巨细胞病毒、单纯疱疹病毒、水痘-带状疱疹病毒）。如何使用更昔洛韦（DHPG）和阿昔洛韦。
Infect Dis Clin North Am. 1988 Jun;2(2):495-509.
3
Detection of cytomegalovirus in urine from newborns by using polymerase chain reaction DNA amplification.利用聚合酶链反应DNA扩增技术检测新生儿尿液中的巨细胞病毒。
J Infect Dis. 1988 Dec;158(6):1177-84. doi: 10.1093/infdis/158.6.1177.
4
The diagnosis of cytomegalovirus retinitis.
Ann Intern Med. 1988 Dec 15;109(12):963-9. doi: 10.7326/0003-4819-109-12-963.
5
Persistence of cytomegalovirus in mononuclear cells in peripheral blood from blood donors.献血者外周血单个核细胞中巨细胞病毒的持续存在。
BMJ. 1989 Oct 7;299(6704):897-8. doi: 10.1136/bmj.299.6704.897.
6
Demonstration of HIV-1 and HHV-6 in AIDS-associated retinitis.人类免疫缺陷病毒1型和人疱疹病毒6型在艾滋病相关性视网膜炎中的表现
Curr Eye Res. 1989 Apr;8(4):379-87. doi: 10.3109/02713688908996385.
7
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J Med Virol. 1986 Oct;20(2):177-82. doi: 10.1002/jmv.1890200209.
8
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Arch Ophthalmol. 1991 Feb;109(2):266-71. doi: 10.1001/archopht.1991.01080020112054.
9
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