Konuk Numan, Kiran Sibel, Tamam Lut, Karaahmet Elif, Aydin Hüner, Atik Levent
Turk Psikiyatri Derg. 2007 Summer;18(2):147-54.
The aims of the study were to validate the Turkish version of the Mood Disorder Questionnaire (MDQ) as a screening tool and to determine its optimum cut-off value for bipolar disorder.
Validation of the Turkish version of the MDQ was conducted on a sample of 309 consecutive patients who attended the psychiatry outpatient unit of 2 different university hospitals. The Structured Diagnostic Interview for DSM-IV Axis I Disorders (SCID) was used as a gold standard test and receiver operating characteristic (ROC) analysis was used to evaluate test performance of the MDQ.
In all, 36 (11.7%) patients received a diagnosis of bipolar disorder (type I and II, and bipolar disorder not otherwise specified), 185 (86.1%) were diagnosed as having at least one Axis I psychiatric disorder other than bipolar disorder, and 7 (2.2%) had no psychiatric disorder according to SCID results. Sensitivity and specificity results indicated that the best Turkish MDQ cut-off point was 7 (sensitivity: 0.64; specificity: 0.77), the cut-off point 5 had 0.81 sensitivity and 0.53 specificity, and the cut-off 6 had 0.75 sensitivity and 0.63 specificity.
The Turkish MDQ has satisfactory psychometric properties for screening bipolar disorder. The psychometric properties of the Turkish MDQ and its ease of use make it a useful tool for screening bipolar disorders, though further population-based research is required to confirm these results.
本研究旨在验证土耳其语版心境障碍问卷(MDQ)作为一种筛查工具的有效性,并确定其用于双相情感障碍的最佳临界值。
对连续就诊于两家不同大学医院精神科门诊的309例患者进行了土耳其语版MDQ的有效性验证。采用《精神障碍诊断与统计手册》第四版轴I障碍结构化诊断访谈(SCID)作为金标准测试,并使用受试者工作特征(ROC)分析来评估MDQ的测试性能。
根据SCID结果,共有36例(11.7%)患者被诊断为双相情感障碍(I型和II型,以及未另行说明的双相情感障碍),185例(86.1%)被诊断为患有除双相情感障碍以外的至少一种轴I精神障碍,7例(2.2%)无精神障碍。敏感性和特异性结果表明,土耳其语版MDQ的最佳临界值为7(敏感性:0.64;特异性:0.77),临界值5的敏感性为0.81,特异性为0.53,临界值6的敏感性为0.75,特异性为0.63。
土耳其语版MDQ在筛查双相情感障碍方面具有令人满意的心理测量学特性。土耳其语版MDQ的心理测量学特性及其易用性使其成为筛查双相情感障碍的有用工具,不过需要进一步基于人群的研究来证实这些结果。